ALS Patient-derived iPSC Models for Advancing Drug Discovery
Time: 2:00 pm
day: Conference Day One Track A PM
Details:
- Development of targeted disease modifying therapeuticsDevelopment of multiple neuronal & glial cell types from healthy and disease patient iPSC lines
- TDP43 mislocalization in ALS-patient iPSC derived motor neuron
- Current capabilities and potential future applications in advancing personalized medicine for ALS disease & other neurodegenerative diseases
- Demonstrating how these models improve target discovery, biomarker validation, and preclinical predictability in drug development