Anil Tarachandani

Company: Verge Genomics

Job title: Vice President and Head of Translational Medicine

Seminars:

Learning from the Past: A Landscape Analysis of Recent Failures in ALS Drug Development to Inform Future Successes 1:00 pm

Overviewing key readouts of recent clinical failures to uncover pitfalls in ALS drug development to quicken the pace of research Examining key challenges in ALS development, including translational gaps in preclinical models, ineffective patient stratification, and trial design issues that hinder clinical success Highlighting the importance of biomarker-driven strategies, multi-omics integration and adaptive trial designs…Read more

day: Conference Day One Track B PM

Panel Discussion: Given Recent Failures, How Can we Tailor ALS Clinical Trials to Successfully Meet Regulatory Expectations 1:30 pm

Outlining the approval path for sporadic and familial ALS: is it the same for different modalities? What is the regulatory bar for approving this? Harnessing innovative trial design Cross comparing diverging requirements for different regulatory agencies including the FDA, EMA and more Establishing clear, patient-relevant endpoints and leveraging biomarkers to demonstrate efficacy Critically identifying stumbling…Read more

day: Conference Day One Track B PM