Makoto Tamura

Makoto Tamura

Company: Mitsubishi Tanabe Pharma

Job title: Senior Director, NeuroDiscovery Lab

Seminars:

Modeling ALS Pathophysiology Using Patient-Derived iPSCs for Therapeutic Insights 10:30 am

Establishing patient-derived iPSC-neurons harboring TDP-43 mutations, providing a robust in vitro model to recapitulate key pathological features of ALS Comprehensive analyses to investigate the mechanisms of action of currently available ALS therapies, offering deeper insights into their therapeutic impact Identifying novel drug targets, paving the way for the development of innovative treatments for ALSRead more

day: Conference Day One Track A

Panel Discussion: To What Extent are In Vivo Models Relevant Purely in Evaluating Toxicity & Target Engagement? 11:30 am

Highlighting the need for robust toxicity and bioavailability data showcased in vivo systems Critically evaluating the ability of animal models to predict drug efficacy in treating ALS patients, and the relevance of target engagement data in vivo with different modalities of treatment (including gene therapies) Navigating regulator perspective across FDA, EMA and more to the…Read more

day: Conference Day One Track A

A Hanson Wade Group Company

© Copyright 2025 Hanson Wade | Design and site by Event Engine | Hanson Wade Limited is registered in England & Wales, number 06752216.
Registered Office: Eastcastle House, 27/28 Eastcastle Street, London, W1W 8DH.