Philip Wong

Company: Johns Hopkins University

Job title: Professor of Pathology

Seminars:

Refining Sensitivity & Specificity of TDP-43 Loss of Function Assay in Plasma for Sporadic ALS for Diagnostic & Trial Utility 8:00 am

Outlining HDGFL2 cryptic neoepitope as a potential early diagnostic marker for ALS, identifying TDP-43 splicing repression in plasma of sporadic ALS patients, upstream of aggregate formation Harnessing TDP-43 splicing repression to identify ALS onset upstream of aggregate pathology and earlier in disease for earlier diagnosis Evaluating longitudinal changes in disease progression and patient benefit to…Read more

day: Conference Day Two

Workshop A: Pioneering Modalities for ALS: Unpacking the Gene Therapy Toolbox & Beyond 9:00 am

From gene editing and augmentation to emerging delivery systems and knockdown strategies, the session will provide a comprehensive exploration of the gene therapy landscape. Participants will discuss which technologies are best suited for targeting specific ALS mutations, the challenges of sporadic versus hereditary forms, and the broader application of current platforms. By analyzing both successes…Read more

day: Pre Conference Day Workshop Track A