Advancing ALS & FTD Functional Phenotyping with Next-Generation High-Density Microelectrode Arrays
- Using HD-MEA functional readouts from human iPSC-derived ALS and FTD models to quantify disease-relevant activity patterns that can inform therapeutic screening and functional rescue studies
- Uncovering treatment windows for functional rescue experiments by resolving disease-specific network, singleneuron, and axonal alterations in TDP-43 and GRN-linked neurodegeneration
- Delivering scalable, automated HD-MEA workflows to generate reproducible functional data applicable to longitudinal profiling, therapeutic screening, and industry collaborations