Advancing Nucleic Acid Therapies for ALS: Delivery Innovations, Multiomic Insights, & Next-Generation Target Discovery
- Learnings from full-cycle oligonucleotide development in ALS, spanning target validation, lead identification, and clinical candidate nomination
- Delivery innovations and nucleic-acid–based strategies that may improve therapeutic reach and durability in neurodegenerative disease
- How integrated data science, including bioinformatics, computational biology, and biomarker discovery, is shaping next-generation ALS programs
- The role of multiomic and spatial biology platforms in enabling precision medicine approaches for ALS and other neurodegenerative disorders